2012-03-30Combined toxicokinetic and 'in vivo' genotoxicity study on Alternaria toxins (European Food Safety Authority (EFSA))
The present call aims to generate data to fill the information gaps in the fields of toxicokinetics and genotoxicity and allowing for the refinement of the risk assessment on Alternaria toxins. The scientific opinion indicated that, among the potentially genotoxic Alternaria toxins, AOH occurs with a relatively high frequency in foodstuffs. In particular, AOH has shown positive results when tested in mutagenicity and clastogenicity assays 'in vitro' both in bacteria and mammalian cell systems. No 'in …
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