2022-06-16   ADME4NGRA: Implementing the EFSA NAMs Roadmap through Advancing Toxicokinetic Knowledge in Chemical Risk Assessment (European Food Safety Authority (EFSA))
The aim of this procurement is to execute a project to support the development of advanced in vitro and in silico ADME (absorption, distribution, metabolism and excretion) models and databases for next generation risk assessment (NGRA) of chemicals using illustrative case studies. Visualizza l'appalto »
Fornitori citati: esqLABS GmbH Fraunhofer-Gesellschaft zur Foerderung... French Agency for Food, Environmental and... German Federal Institute of Risk Assessment Istituto di Ricerche Farmacologiche Mario Negri Istituto Superiore di Sanità Rheinische Friedrich-Wilhelms-Universität Bonn Stichting VU Stichting Wageningen Research TissUse GmbH Wageningen University, dep....

2020-01-13   Mechanistic Analysis of Repeated Dose Toxicity Studies (European Commission, JRC — Joint Research Centre, JRC.F — Health, Consumers and Reference Materials (Geel), JRC.F.3 — Chemicals )
Contract to harvest and analyse mechanistic knowledge related to target organ toxic effects after repeated exposure. The results will feed into EURL ECVAM activities aimed at developing an alternative approach to study systemic toxicity after repeated exposure that is motivated by a better understanding of the mechanisms involved and their human relevance. Visualizza l'appalto »
Fornitori citati: Stichting VU